Basic Product Information
Source and Extraction: Matrine 99 pure Plant Extract for research is an alkaloid extracted from the roots, stems, and leaves of Sophora flavescens (a Fabaceae plant) using modern separation and purification technologies, with a purity of up to 99%. As one of the main active components of Sophora flavescens, its extraction process strictly controls raw material quality and process parameters to ensure the naturalness and stability of the ingredient. Chemical Properties: Chemically known as matridin, with the molecular formula C₁₅H₂₄N₂O, it belongs to quinolizidine alkaloids. It has certain lipophilicity and good solubility in organic solvents, a property that makes it easy to be formulated into various dosage forms to meet different application scenarios.
Core Biological Activities and Efficacies
Broad-Spectrum Antibacterial and Antiparasitic Effects
It inhibits various Gram-positive bacteria, Gram-negative bacteria (e.g., Escherichia coli, Staphylococcus aureus), and fungi. It exerts antibacterial effects by damaging bacterial cell membranes and inhibiting protein synthesis, and is commonly used in veterinary medicine for adjuvant treatment of intestinal infections and skin infections.
It has a paralyzing effect on parasites (e.g., roundworms, tapeworms) by interfering with their energy metabolism, making it an important source of natural anthelmintic ingredients.
Anti-Inflammatory and Immunomodulatory Effects
It can inhibit the release of inflammatory mediators (e.g., histamine, prostaglandins), reduce tissue inflammatory responses, and alleviate chronic inflammations such as skin inflammation and joint inflammation.
It regulates the body’s immune function by enhancing the phagocytic activity of macrophages while moderately inhibiting overactive immune responses, maintaining immune balance.
Antitumor and Antiviral Potential
In vitro studies have shown that Matrine 99 can induce tumor cell apoptosis and inhibit tumor angiogenesis, especially exerting a certain inhibitory effect on liver cancer and gastric cancer cell lines, providing directions for antitumor adjuvant research.
It inhibits some viruses (e.g., herpes virus, coxsackievirus), possibly by interfering with the viral replication cycle.
Agricultural and Environmental Applications
As a natural plant-derived pesticide, it has contact and stomach toxicity effects on pests such as aphids and red spiders. It is low-toxic and easily degradable, conforming to the needs of green agricultural development.
Application Fields
Medicine and Veterinary Medicine: It can be formulated into tablets, injections, and external ointments for adjuvant treatment of infectious and inflammatory diseases; in veterinary medicine, it is often used for the prevention and treatment of intestinal parasitic diseases and skin infections in livestock and poultry.
Daily Chemicals and Skincare: Added to antibacterial hand sanitizers and acne-removing skincare products, it helps improve skin flora balance by virtue of its antibacterial and anti-inflammatory properties.
Agricultural Field: Made into biological pesticides, it is used for pest control in fruits, vegetables, and food crops, reducing chemical pesticide residues.